Isolation of bioactive compounds from hemp (Cannabis sativa L.) by conventional and novel extraction techniques
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Дата
2022
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Анотація
Industrial hemp (Cannabis sativa L.) is a source of valuable bioactive
compounds which is used as a highly valuable product in food, pharmaceutical and
cosmetic industries. Bioactive composition of hemp contributes to the prevention and
treatment of some diseases, so it can be widely used in medicine. The main goal of this
paper was to investigate the most convenient extraction approach for isolation of
bioactive compounds (cannabinoids and phenols) from dry inflorescence of three hemp
varieties. Modern extraction techniques were applied and compared with conventional
techniques in order to obtain maximum yield. Essential oils were obtained by
hydrodistillation (HD), microwave-assisted hydrodistillation (MWHD) and
supercritical fluid extraction (SFE). Extracts from the primary raw material of hemp
and SFE raffinate were processed by microwave-assisted extraction in order to isolate
polyphenolic fraction. The obtained results showed that SFE provides the highest yield
of hemp oil compared to HD and MWHD. The highest yield of lipid extract was
obtained from variety Fedora 13 (14.01%), while the lowest yield was obtained from
variety Marina (5.33%). The high content of phenols and flavonoids obtained from
SFE raffinates indicates that the by-products of supercritical fluid extraction could be
used as potential natural antioxidants.
Опис
Milošević S. Isolation of bioactive compounds from hemp (Cannabis sativa L.) by conventional and novel extraction techniques / S. Milošević ; advisor B. Pavlić // Black Sea Science 2022 : proc. of the Intern. Competition of Student Scientific Works / Odesa National University of Technology ; eds. B. Yegorov, M. Mardar [et al.]. – Odessa : ONUT, 2022. – P. 51–64 : fig. – Ref.: 23 tit.
Ключові слова
Cannabis sativa L., supercritical fluid extraction, microwave assisted extraction, essential oil, polyphenols